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A Closer Look
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RESEARCH GRANT AWARDS

AWARDS LIST.

Totals by Year

2022 - $1,199,966

2021 - $749,812

2020 - $630,000

2019 - $690,000

2018 - $750,000

2017 - $747,772

2016 - $720,000

2015 - $840,000

2014 - $810,000

2013 - $808,500

2012 - $720,000

2011 - $599,780

2010 - $438,000

2009 - $435,000

2008 - $619,993

2007 - $232,600

2006 - $384,551

Shi-Long Lu, MD, PhD and Daniel Frank, PhD

2022

$60,000

Functional assessment of human microbiome in head and neck cancer mouse models

Jeffrey Moore, PhD

2022

$30,000

Mechanism of Chemotherapeutic Resistance by TUBB3 Tubulin

Joselyn Cruz Cruz, PhD

2022

$ 30,000

Reversing Immunosuppression in Rhabdomyosarcoma

Reema Wahdan, PhD and Daniel LaBarbera, PhD

2022

$60,000

Targeting Thyroid Hormone-Mediated Cancer Stem Cell Expansion and Treatment Resistance in ER+ Breast Cancer cells

Keara Boss, DVM, PhD and Steven Dow, DVM, PhD

2022

$60,000

Establishing a novel orthotopic sinonasal carcinoma model in immunocompetent rats for translational radiation and immunotherapy research

Mohamed Ghoneim, PhD

2022

$30,000

Mechanisms of PBAF Remodeling Complex and Effect of Cancer Mutations

Todd Pits, PhD, and Julie Lang, PhD

2022

$60,000

Anti-TIGIT antibody in combination with bevacizumab/DC101 and pembrolizumab in microsatellite stable colorectal cancer

Zdenek Andrysik, PhD

2022

 $ 30,000

Pre-clinical test of colorectal cancer therapy based on combinatorial activation of p53 and Integrated Stress Response

Nathan Dahl, MD and Rajeev Vibhakar, MD, PhD, MPH

2022

$60,000

CDK9 as a druggable mediator sustaining Myc-driven circuitry in medulloblastoma

Yiqun Shellman, PhD and Richard Tobin, PhD

2022

$60,000

Investigating the role of host Sash 1 expression in antitumor Immunity

Eric T. Clambey, PhD and Raphael A. Nemenoff, PhD

2022

$60,000

Role of Cancer-cell specific MHC II in regulating response to immune checkpoint inhibitors in lung cancer

Robert Meguid, MD, PhD, and Christina Stewart, MD

2022

$30,000

Pilot Development of an Enriched Cancer Database using Machine Learning Techniques

Douglas H. Thamm, VMD, DACVIM

2022

$29,997

Antitumor and Antimetastatic Effects of MYC Depletion with Omacetaxine in Osteosarcoma

Paul Jedlicka, MD, PhD

2022

$ 30,000

Understanding new mechanisms cooperating with the PAX3/FOX01 driver oncofusion in rhabdomyosarcoma

Molishree Joshi, PhD, Scott Cramer, PhD, and James Costello, PhD

2022

$60,000

Vitamin D synthetic lethal network across benign and metastatic cell lines

Khosbayar Lkhagvadorj, PhD

2022

$30,000

An ex-vivo organoid model to identify markers of lung adenocarcinoma premalignancy

Sujatha Venkataraman, PhD and Eric Kohler, MD, PhD and Masanori Hayashi, MD

2022

$60,000

Pre-clinical evaluation of "SMART CAR"-T cell therapy against primary and metastatic Ewing sarcoma

Tejas Patil, MD and Lynn Heasley, PhD

2022

$60,000

Programmed death receptor (PD-L1) expression as a biomarker for tyrosine kinase inhibitor (TKI) efficacy among patients with ALK-rearranged NSCLC

Nicholas Foreman, MD

2022

$ 30,000

Integration of single-nuclei RNA-sequencing and spatial transcriptomics to study the transformation of highly aggressive malignant peripheral nerve sheath tumors

Takamitsua Kato, PhD

2022

$30,000

Investigation of mechanisms and feasibility for chemo/radio-sensitization for cancer therapy by SQAP

Jessica Floyd, MD

2022

$30,000

Modulation of the immune suppressed tumor microenvironment in high grade serous ovarian cancer through interventions in the tryptophan catabolism pathway

Martin Barrio, MD, MS

2022

$30,000

Identifying clinical and genetic features associated with thyroid cancer risk of recurrence

Joshua Black, PhD and Heide Ford, PhD

2022

$60,000

Assessing the Prevalence of DNA Rereplication During Epithelial to Mesenchymal Transition in Breast Cancer

Matthew Witkowski, PhD

2022

$30,000

Targeting RNA-binding protein, NUDT21, enhances CD19 abundance on human B-cell acute lymphoblastic leukemia cells

Camille Stewart, MD and Mayumi Fujita, MD, PhD

2022

$59,969

Evaluating the Effects of Cannabis Use and Circulating Cannabinoids on Tumor Infiltrating Lymphocytes in Malignant Melanoma

Jung-Jae Lee, PhD

2022

$ 30,000

Body heat activated storable, near-infrared, self-illuminating nanoprobes for in vivo optical imaging of cancer

Michelle Williams, PhD

2022

$30,000

Targeting Heme Metabolism to Enhance Sensitivity to Immunotherapy in Metastatic Triple-Negative Breast Cancer

John Tentler, PhD

2022

$30,000

Cancer Research Summer Fellowship Program

Nathan Dahl, MD

2021

$30,000

Unlocking the combination: Potentiation of radiation-induced antitumor effect using clinically-relevant BH3 mimetics to effectively target DIPG

Alisa Lee-Sherick, MD and C. Wyatt Shields, PhD

2021

$60,000

Assessment of Cell Types for Delivering MerTK Inhibitors to Sarcomas

Elizabeth Kessler, MD

2021

$29,812

Validation of a patient-reported tool to screen for geriatric impairments predictive of potential frailty in cancer patients

Santos Franco, PhD, Siddhartha Mitra, PhD and Adam Green, MD

2021

$60,000

Development of In utero driven Mouse Models of Diffused Midline Gliomas to study the tumor immune interactions in Pediatric Midline Gliomas

Paul Jedlicka, MD, PhD

2021

$30,000

Understanding the metastasis-promoting cistrome in Ewing Sarcoma

Sujatha Venkataraman, PhD

2021

$30,000

Novel CAR T cell therapies to target metastatic Ewing Sarcoma

Adam Green, MD and Natalie Serkova, PhD and Mark Borden, PhD

2021

$60,000

MRI-Guided Focused Ultrasound to Improve Treatment of DIPG

Andrew Getahun, PhD and John Cambier, PhD

2021

$60,000

Identification of novel inhibitory checkpoint receptors

Carlo Marchetti, PhD and Mayumi Fujita, MD, PhD

2021

$60,000

Identifying the role of NLRP3 in immunotherapy resistant melanomas

Leonora Slatnick, MD

2021

$30,000

Biomarker Development for Sepsis in Pediatric Oncology Patients

Jennifer Matsuda, PhD and James Scott-Browne, PhD

2021

$60,000

Genetic manipulation of human T cell transcriptional programs to improve cancer immunotherapy

Satyanarayan Rao, PhD

2021

$30,000

Using transcription factors to map tumor state and microenvironment

John Tentler, PhD

2021

$30,000

Cancer Research Summer Fellowship Program

Carol Sartorius, PhD

2021

$30,000

Lipodependence of endocrine resistant breast cancer as a therapeutic target

Matthew J. Sikora, PhD

2021

$30,000

Targeting an unexplored DNA repair deficiency and radiosensitivity in lobular breast cancer

Masanori Hayashi, MD

2021

$30,000

Preclinical Investigation of BCOR rearranged solid tumors

Rajeev Vibhakar, MD, PhD, MPH

2021

$30,000

Role of BMI1 in SMARB1 deleted ATRTs

Siddhartha Mitra, PhD

2021

$30,000

Development of Chimeric Antigen Receptor Expressing macrophages and microglia to target pediatric glioblastoma

Takeshi Yamauchi, PhD

2021

$30,000

Non-UV risk factors of melanoma

Raphael Nemenoff, PhD & Erin Schenk, MD, PhD

2020

 $     60,000

The Tumor Microenvironment as a Critical  Regulator of Targeted Therapy in ALK Positive Lung Cancer

Mayumi Fujita, MD, PhD & Charles A. Dinarello, MD

2020

 $     60,000

The role of alpha-1 antitrypsin in cancer immunotherapy

Sujatha Venkataraman PhD & Adam Green, MD & Mark Kohler, MD, PhD

2020

 $     60,000

Engineering Logic-Gated DC99 CAR to selectively target H3K27M-DIPG tumor cells and to protect normal cells

Christine Towers, PhD

2020

 $     30,000

Identifying novel regulators of mitochondrial turn over

Maureen Lynch, Phd & Philip Owens, PhD

2020

 $     60,000

The role of exercise in breast cancer bone metastasis

Rebecca Schweppe, PhD

2020

 $     30,000

The role of Nuclear FAK in Thyroid Cancer

Diana M. Cittelly, PhD

2020

 $     30,000

Function of Ephrin B Signaling in Breast cancer brain metastasis

Matthew Tallaferro, PhD

2020

 $     30,000

Control of cell division through centrosomal RNA localization

Molishree Joshi, PhD

2020

 $     30,000

A novel CRISPR-mediated tumor targeting strategy for Liiposarcoma

Swati G. Patel, MD, MS

2020

 $     30,000

Identification of Hereditary Cancer Syndromes through Advanced Polyps

Zachary Graff, MD

2020

 $     30,000

Development of Bispecific CAR T-cells for the Prevention of Lineage Switch in KMT2A-rearranged Leukemia

Breelyn Wilky, MD & Eduardo Davila, PhD

2020

 $     60,000

Toxicity and Biodistribution of CD*:MyD88 Engineered Autologous T Cells In Mouse Models of Melanoma and Fibrosarcoma

Senthilnath Lakshmana Chetty, PhD

2020

 $     30,000

Combining radiation and Immunotherapy to target diffuse midline gliomas with the H3K27M mutation

Zdenek Andrysik PhD

2020

$ 30,000

Exploring strong synergism of targeted p53 activation and translation inhibition in colorectal cancer.

Ryan Marker, PhD

2020

 $     30,000

Feasibility and effectiveness of an Innovative exercise program to reduce fatigue in rural cancer survivors

Paula Jedlicka, MD, PhD

2020

 $     30,000

Understanding and targeting highly metastatic EWS/FLi1-low cells in Ewing Sarcoma

Matthew Sikora, PhD

2019

 $              30,000

Defining MDC1 as a central regulator of estrogen receptor and DNA repair in lobular carcinoma

Stephen Keysar, PhD

2019

 $              30,000

Targeting of stemness factors and fusion proteins in salivary gland cancers through inhibition of translation elongation

Rajeev Vibhakar, MD, PhD, MPH

2019

 $              30,000

Role of CDK7 in medulloblastoma

Neelanjan Mukherjee, PhD & Daniel Sherbenou, MD, PhD

2019

 $              60,000

Exploiting mRNA translation inhibition for the treatment of relapsed/refractory multiple myeloma

Neil Box, PhD

2019

 $              30,000

Regulation of p53 in tanning

Mayumi Fujita, MD, PhD  & Donald Backos, PhD

2019

 $              60,000

Somatic mutations in inflammasome genes in melanoma

Yiqun Shellman, PhD & Martin McCarter, MD

2019

 $              60,000

Targeting anti-apoptotic pathways to improve immunotherapies for melanoma

Shi-Long Lu, MD, PhD and Daniel Frank, PhD

2019

 $              60,000

Mechanism of oral microbiota in head and neck cancer pathogenesis and application for targeted therapy

Sujatha Venkataraman, PhD and Mark Kohler, MD, PhD

2019

 $              60,000

CD99 targeting CAR T cells as a novel therapy for H3K27M mutant DIPG

Jay Hesselberth, PhD

2019

 $              30,000

Single-cell methods to measure functional heterogeneity

Adam Mueller, MD, PhD

2019

 $              30,000

Investigating crosstalk between ADAM10 and EphrinB2/EPHB4 in mediating radiation induced fibrosis, invasion and metastasis in pancreatic cancer

John Tentler, PhD

2019

 $              30,000

Cancer Research Summer Fellowship Program

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