A Closer Look
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RESEARCH GRANT AWARDS

AWARDS LIST.

Totals by Year

2021 - $749,812

2020 - $630,000

2019 - $690,000

2018 - $750,000

2017 - $747,772

2016 - $720,000

2015 - $840,000

2014 - $810,000

2013 - $808,500

2012 - $720,000

2011 - $599,780

2010 - $438,000

2009 - $435,000

2008 - $619,993

2007 - $232,600

2006 - $384,551

Nathan Dahl, MD

2021

$30,000

Unlocking the combination: Potentiation of radiation-induced antitumor effect using clinically-relevant BH3 mimetics to effectively target DIPG

Carol Sartorius, PhD

2021

$30,000

Lipodependence of endocrine resistant breast cancer as a therapeutic target

Carlo Marchetti, PhD and Mayumi Fujita, MD, PhD

2021

$60,000

Identifying the role of NLRP3 in immunotherapy resistant melanomas

Santos Franco, PhD, Siddhartha Mitra, PhD and Adam Green, MD

2021

$60,000

Development of In utero driven Mouse Models of Diffused Midline Gliomas to study the tumor immune interactions in Pediatric Midline Gliomas

Paul Jedlicka, MD, PhD

2021

$30,000

Understanding the metastasis-promoting cistrome in Ewing Sarcoma

Leonora Slatnick, MD

2021

$30,000

Biomarker Development for Sepsis in Pediatric Oncology Patients

Adam Green, MD and Natalie Serkova, PhD and Mark Borden, PhD

2021

$60,000

MRI-Guided Focused Ultrasound to Improve Treatment of DIPG

Jennifer Matsuda, PhD and James Scott-Browne, PhD

2021

$60,000

Genetic manipulation of human T cell transcriptional programs to improve cancer immunotherapy

Matthew J. Sikora, PhD

2021

$30,000

Targeting an unexplored DNA repair deficiency and radiosensitivity in lobular breast cancer

Satyanarayan Rao, PhD

2021

$30,000

Using transcription factors to map tumor state and microenvironment

John Tentler, PhD

2021

$30,000

Cancer Research Summer Fellowship Program

Elizabeth Kessler, MD

2021

$29,812

Validation of a patient-reported tool to screen for geriatric impairments predictive of potential frailty in cancer patients

Rajeev Vibhakar, MD, PhD, MPH

2021

$30,000

Role of BMI1 in SMARB1 deleted ATRTs

Siddhartha Mitra, PhD

2021

$30,000

Development of Chimeric Antigen Receptor Expressing macrophages and microglia to target pediatric glioblastoma

Andrew Getahun, PhD and John Cambier, PhD

2021

$60,000

Identification of novel inhibitory checkpoint receptors

Masanori Hayashi, MD

2021

$30,000

Preclinical Investigation of BCOR rearranged solid tumors

Takeshi Yamauchi, PhD

2021

$30,000

Non-UV risk factors of melanoma

Alisa Lee-Sherick, MD and C. Wyatt Shields, PhD

2021

$60,000

Assessment of Cell Types for Delivering MerTK Inhibitors to Sarcomas

Sujatha Venkataraman, PhD

2021

$30,000

Novel CAR T cell therapies to target metastatic Ewing Sarcoma

Senthilnath Lakshmana Chetty, PhD

2020

 $     30,000

Combining radiation and Immunotherapy to target diffuse midline gliomas with the H3K27M mutation

Breelyn Wilky, MD & Eduardo Davila, PhD

2020

 $     60,000

Toxicity and Biodistribution of CD*:MyD88 Engineered Autologous T Cells In Mouse Models of Melanoma and Fibrosarcoma

Zachary Graff, MD

2020

 $     30,000

Development of Bispecific CAR T-cells for the Prevention of Lineage Switch in KMT2A-rearranged Leukemia

Christine Towers, PhD

2020

 $     30,000

Identifying novel regulators of mitochondrial turn over

Paula Jedlicka, MD, PhD

2020

 $     30,000

Understanding and targeting highly metastatic EWS/FLi1-low cells in Ewing Sarcoma

Zdenek Andrysik PhD

2020

30,000

Exploring strong synergism of targeted p53 activation and translation inhibition in colorectal cancer.

Matthew Tallaferro, PhD

2020

 $     30,000

Control of cell division through centrosomal RNA localization

Ryan Marker, PhD

2020

 $     30,000

Feasibility and effectiveness of an Innovative exercise program to reduce fatigue in rural cancer survivors

Diana M. Cittelly, PhD

2020

 $     30,000

Function of Ephrin B Signaling in Breast cancer brain metastasis

Molishree Joshi, PhD

2020

 $     30,000

A novel CRISPR-mediated tumor targeting strategy for Liiposarcoma

Sujatha Venkataraman PhD & Adam Green, MD & Mark Kohler, MD, PhD

2020

 $     60,000

Engineering Logic-Gated DC99 CAR to selectively target H3K27M-DIPG tumor cells and to protect normal cells

Swati G. Patel, MD, MS

2020

 $     30,000

Identification of Hereditary Cancer Syndromes through Advanced Polyps

Rebecca Schweppe, PhD

2020

 $     30,000

The role of Nuclear FAK in Thyroid Cancer

Raphael Nemenoff, PhD & Erin Schenk, MD, PhD

2020

 $     60,000

The Tumor Microenvironment as a Critical  Regulator of Targeted Therapy in ALK Positive Lung Cancer

Mayumi Fujita, MD, PhD & Charles A. Dinarello, MD

2020

 $     60,000

The role of alpha-1 antitrypsin in cancer immunotherapy

Maureen Lynch, Phd & Philip Owens, PhD

2020

 $     60,000

The role of exercise in breast cancer bone metastasis

Isabel Schlaepfer, PhD

2019

 $              30,000

Role of fat oxidation via CPT1A in immunological response to prostate cancer

Rajeev Vibhakar, MD, PhD, MPH

2019

 $              30,000

Role of CDK7 in medulloblastoma

Jay Hesselberth, PhD

2019

 $              30,000

Single-cell methods to measure functional heterogeneity

John Tentler, PhD

2019

 $              30,000

Cancer Research Summer Fellowship Program

Matthew Sikora, PhD

2019

 $              30,000

Defining MDC1 as a central regulator of estrogen receptor and DNA repair in lobular carcinoma

Zachary Levi Watson, PhD

2019

 $              30,000

Targeting histone acetylation in PARP inhibitor-resistant ovarian cancer

Stephen Keysar, PhD

2019

 $              30,000

Targeting of stemness factors and fusion proteins in salivary gland cancers through inhibition of translation elongation

Cem Altunbas, PhD

2019

 $              30,000

High-fidelity volumetric imaging for quantitative treatment monitoring and modifications in radiation therapy

Yiqun Shellman, PhD & Martin McCarter, MD

2019

 $              60,000

Targeting anti-apoptotic pathways to improve immunotherapies for melanoma

Paul Norman, PhD

2019

 $              30,000

Natural Killer cells can protect from developing leukemia

Heather Brechbuhl, PhD

2019

 $              30,000

Defining reversible tumor traits in the obese microenvironment

Neelanjan Mukherjee, PhD & Daniel Sherbenou, MD, PhD

2019

 $              60,000

Exploiting mRNA translation inhibition for the treatment of relapsed/refractory multiple myeloma

Shi-Long Lu, MD, PhD and Daniel Frank, PhD

2019

 $              60,000

Mechanism of oral microbiota in head and neck cancer pathogenesis and application for targeted therapy

Mayumi Fujita, MD, PhD  & Donald Backos, PhD

2019

 $              60,000

Somatic mutations in inflammasome genes in melanoma

Neil Box, PhD

2019

 $              30,000

Regulation of p53 in tanning

Carol Sartorius, PhD

2019

 $              30,000

PR-RAR downregulation of protein synthesis and cell growth in breast cancer

Adam Mueller, MD, PhD

2019

 $              30,000

Investigating crosstalk between ADAM10 and EphrinB2/EPHB4 in mediating radiation induced fibrosis, invasion and metastasis in pancreatic cancer

Sujatha Venkataraman, PhD and Mark Kohler, MD, PhD

2019

 $              60,000

CD99 targeting CAR T cells as a novel therapy for H3K27M mutant DIPG

Jill Slansky PhD

2018

 $     30,000

Functional activation of low-affinity T cells in the tumor

Adwitiya Kar, PhD and Margaret Wierman, MD

2018

 $     30,000

Targeting Maternal Embryonic Leucine Zipper Kinase (MELK) in the first pre-clinical models of Adrenocortical Carcinoma

Maria Jose Contreras, PhD

2018

 $     30,000

Mechanisms of TDM1/radiation-induced toxicity in brain metastases

John Tentler, PhD

2018

 $     30,000

Cancer Research Summer Fellowship Program

Mair E.A. Churchill, PhD

2018

 $     30,000

Inhibition of Chromatin Assembly Factor 1 B to Reverse Leukemogenesis

Courtney Jones, PhD

2018

 $     30,000

Targeting relapse leukemia stem cells through inhibition of NAD synthesis

Linda Van Dyk, PhD

2018

 $     30,000

Role of CDK4 and CDK6 in gammaherpesvirus oncogenesis

Nicholas Forman, MD

2018

 $     30,000

Characterization of heterogeneous tumor subpopulations in childhood ependymoma

Zhangguo Chen, PhD

2018

 $     30,000

Elucidating mechanisms by which a newly developed HDAC inhibitor sensitizes B cell lymphomas to PD-1 therapy

Nathan Dahl, MD

2018

 $     30,000

Oncogenic Role of the Super Elongation Complex in H3K27M-mutant Diffuse Midline Glioma

Christopher Lieu, MD and Todd Pitts, MD

2018

 $     60,000

Investigating the role of MEK and non-canonical Wnt inhibition in altering the immune microenvironment in metastatic colorectal cancer

Jennifer DeLuca, PhD

2018

 $     30,000

Targeting Kinetochore Dysfunction in Cancer Cells

Raul M. Torres, PhD

2018

 $     30,000

Suppression of human CD8 T cell antigen receptor signaling and cytotoxic activity by lysophosphatidic acid

Rebecca Schweppe, PhD

2018

 $     30,000

Cooperative Src and MAP Kinase Signaling in Thyroid Cancer

David Thomas, PhD and Mark Borden, PhD

2018

 $     30,000

X-Ray Acoustic Computed Tomography Guided Adaptive Radiotherapy

Benjamin Bitler, PhD

2018

 $     30,000

Investigating the mechanisms of EHMT1/2-dependent PARP inhibitor resistance

David Ryan Ormond MD

2018

 $     30,000

Diffusion tensor image tractography in surgical resection of glioblastoma resection and surgical safety

Katja Kiseljak-Vassiliades, DO and Kimberly Jordan, PhD

2018

 $     60,000

Potentiating anti-PD1 Immunotherapy with Mitotane in Adrenocortical Carcinoma

Martin McCarter, MD

2018

 $     30,000

Improving immune checkpoint inhibitor efficacy by targeting myeloid-derived suppressor cell function

Jessica Lake, MD, MPH

2018

 $     30,000

IPS-derived, CAR-expressing Natural Killer Cells Targeting EGFR on Pediatric Sarcomas

Scott Cramer, PhD and James Costello, PhD

2018

 $     60,000

Targeting the Achilles heel of prostate cancer with loss of CHD1 and MAP3K7

Jennifer Hintzsche, PhD

2018

 $     30,000

Patient-centric Multi-Omics Approach to Identifying Actionable Therapeutics in Cancer