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A Closer Look

RESEARCH GRANT AWARDS

AWARDS LIST.

Totals by Year

2025 - $1,019,994

2024 - 1,139,000
2023 - $891,364

2022 - $1,199,966

2021 - $749,812

2020 - $630,000

2019 - $690,000

2018 - $750,000
2017 - $747,772

2016 - $720,000

2015 - $840,000

2014 - $810,000

2013 - $808,500

2012 - $720,000

2011 - $599,780

2010 - $438,000

2009 - $435,000

2008 - $619,993

2007 - $232,600

2006 - $384,551

Amounts flagged (*) below are funded by Cancer League of Colorado and a generous matching grant from MDC/Richmond American Homes Foundation

Todd Hankinson MD - CO-PI Siddhartha Mitra, PhD - CO-PI

Advancing next generation models for Craniopharyngioma

$60,000

2025

Heather Brechbuhl, PhD Jessica Finlay-Schultz, PhD

Targeting SDC2-Mediated Platelet-Tumor Cell Interactions to Block Breast Cancer Metastasis

$60,000

2025

Austin Gillen, PhD (Co-PI) James DeGregori, PhD, (Co-PI) Michael Alberti, MD, PhD (Co-PI)

Exploring the mechanisms underlying aging-dependent selection for hematopoietic malignancy associated mutations in U2AF1

$59,994

2025

Sheera Rosenbaum, PhD (PI-Fellow) Heide L. Ford, PhD (Mentor)

Elucidating Novel Mechanisms of NK Cell Suppression in metastatic breast cancer

$30,000

2025

Maria Cecilia Caino, PhD

Novel Roles of GCN2 in metastatic prostate cancer

$30,000

2025

Lynn Heasley, PhD Raphael Nemenoff, PhD

Defining the interplay of tumor heterogeneity and the immune microenvironment in determining targeted therapy responses of lung adenocarcinoma

$60,000

2025

Takamitsu Kato, PhD (PI)

CDK11 mutation and genomic instability and cancer predisposition

$30,000

2025

Joshua Thurman, MD (Co-PI) Gina Bouchard, PhD (Co-PI)

Immune Amplification to Target Lung Cancer

$60,000

2025

Joselyn Cruz Cruz, PhD (PI - Fellow) Michael R. Veneris, MD (Mentor)

TAM Receptor Inhibition to Enhance CAR-T Cell Therapy in Pediatric Sarcomas

$30,000

2025

Wenjuan Liao, PhD (PI-Fellow) Patricia Ernst, PhD (Mentor)

Defining the Distinct Biology and Therapeutic Vulnerabilities of Lineage-switched AML following CAR T Relapse

$30,000

2025

Jen Cimons, PhD (PI - Fellow) Michael R. Veneris, MD (Mentor)

JAKed Up for Tolerance: A Ruxolitinib-Based Strategy for Allogeneic CAR T Persistence

$30,000

2025

Laurel Hind, PhD (Co-PI) Richard Tobin, PhD (CoPI)

Uncovering the Role of MDSC-Driven Mitochondrial Transfer in Metabolic Shifts and Immunoresistance in Melanoma

$60,000

2025

Joseph L. Sottnik, PhD (Co-PI) Maria Jose Contreras-Zárate, PhD (Co-PI)

Exploring mechanisms of bone and brain metastases in lobular breast cancer

$60,000

2025

Maggie Musick PhD (PI - Fellow) Matthew J. Sikora, PhD (Mentor)

Defining Drivers of CDH1 loss-induced mammary lineage remodeling and oncogenesis

$30,000

2025

Michael Graner, PhD

Blocking chordoma invasion with phage peptides against chordoma cells and extracellular vesicles

$30,000

2025

Jeffrey Moore, PhD

“Precision tools for disrupting the cytoskeleton in metastatic cancer

$30,000

2025

Reema Wahdan-Alaswad, PhD Jennifer Richer, PhD

Thyroid Hormone and Androgen Receptor Cross-Talk Induces a Poor Prognosis in Estrogen Receptor-Positive Breast Cancer

$60,000

2025

Zhirui Wang, DVM, PhD (PI) Hatim Sabaawy, MD (Co-PI)

Bivalent CD47 Immunotoxin for Targeted Therapy of Lung Cancer

$60,000

2025

John Tentler, PhD

Summer Fellowship Program

$30,000

2025

Paul A. Roberson, PhD, (Co-PI) Andrea Bonetto, PhD (Co-PI)

Sestrin 1 attenuates muscle wasting in cancer cachexia

$60,000

2025

Vincent Chen, PhD (PI-Fellow); M. Eric Kohler, MD, PhD (Co-PI) Siddhartha Mitra, PhD (Mentor)

Targeting Glioblastoma with Augmented anti-B7H3 CARMacrophage Therapy in Immunocompetent Murine Models

$30,000

2025

Matthew Witkowski, Ph.D.(PI)

Dissecting long-chain fatty acid transport as a mechanism of acute lymphoblastic lukemia chemotherapy resistance

$30,000

2025

Kyle Concannon, MD (Co-PI) Peter Fettci MD, PhD (Co-PI)

Overcoming ALK TKI Resistance with EGFR-Targeting, BiTE-Secreting Car T Cell Therapy

$60,000

2025

John Tentler, PhD

Cancer Research Summer Fellowship Program

$30,000

2024

Mercedes Rincon, Ph.D. PI; Craig Jordan Ph.D. Co-PI

Overcoming AML Resistance to VEN-AZA by inhibiting Complex I Activity with MCJ Mimetics

$60,000

2024

Rebecca Schweppe, PhD

Targeting FAK and Ribosome Biogenesis in thyroid cancer

$30,000

2024

Benjamin Bitler, PhD

Overcoming Therapy Resistance via EHMT1/2 Targeting

$30,000

2024

Andrea Bonetto, PhD

PRPS1 is a new mediator of skeletal muscle atrophy in cancerinduced cachexia

$30,000

2024

Shi-Long Lu, MD, PhD Daniel Frank, PhD

Microbiota in the immunotherapy response of oral squamous cell carcinoma

$60,000

2024

Christine Walsh, MD

CU-GENES (CU Genetic Engagement, Education, Screening

$30,000

2024

Robin Dowell, D.Sc; Esteban J Rozen

PAK2 inhibition of Myc oncogenes as a novel therapeutic option for pediatric cancer.

$30,000

2024

James DeGregori, PhD; Jonathan Kurche, M.D., Ph.D

Mutation-driven Clonal expansions as both seed and soil in lung cancer initiation

$30,000

2024

Catherine Danis, PhD

Examining the metabolic fitness of the Adjunctive LATactivating CAR T cell against Acute Myeloid Leukemia

$30,000

2024

Allison J. L’Hotta, PhD, OTD

Fatigue Screening and Triage for the management of Pediatric cancer-related fatigue (FAST-PEDS)

$30,000

2024

Jung-Jae Lee, PhD

Precision Surgery in Head and Neck Cancer with advanced Chemiluminescent Nanoprobes

$30,000

2024

Charlotte Feddersen, MD, PhD, PI (Fellow);Adam Green, MD, (Mentor)

Combination XPO1 Inhibition and Cellular Immunotherapy for the Treatment of Pediatric High-Grade Gliomas

$30,000

2024

Sabrina L Spencer, PhD

Identification of kinase inhibitors that exhibit off-target activation of the Integrated Stress Response

$30,000

2024

Daniel LaBarbera, PhD, PI; Farnoush Banaei-Kashani, Ph D, Co-PI

AI-powered Drug Discovery focused on developing best-in Class KDM4 Inhibitors to advance Epigenetic therapy for Metastatic Colon Cancer

$60,000

2024

Joshua C Black, PhD; Heide Ford, PhD

Determining, Identifying and Controlling Copy Number of Mesenchymal Genes During Epithelial to Mesenchymal Transition in Breast Cancer

$30,000

2024

Joe Nassour, PhD

Investigating the telomere-mitochondria connection in age-associated tumorigenesis

$30,000

2024

Dinoop Ravindran Menon, PhD, CO-PI; Sharon R. Pine, PhD, CO-PI

Targeting OCT1 mediated adaptive resistance in K-RAS mutant LUAD

$60,000

2024

Kole DeGolier, Ph.D CO-PI Fellow;James Scott-Browne, Ph.D. CO-PI - Mentor; Terry Fry, M.D CO-PI

Single cell functional genomics to track transcriptional fate of CAR-T cell responses to leukemia

$60,000

2024

James Costello, PhD

Assessing the phenotypic effects of innervation in bladder cancer

$30,000

2024

Steven Dow, DVM, PhD (PI); Kathryn Wotman, DVM. (Co-PI);Lynn Pezzanite, DVM, PhD (Co-PI)

Equine Model of Penile Carcinoma for Evaluation of Immune Responses to Novel Intratumoral Immunotherapy

$29,999

2024

Neelanjan Mukherjee, PhD; Heide Ford, PhD

Defining and targeting stress-induced translational control as a means to inhibit metastasis

$60,000

2024

Carol Sartorius, PhD Heather Brechbuhl, PhD

Mechanisms and vulnerabilities of fatty acid metabolism in endocrine resistant breast cancer

$60,000

2024

Michael Alberti, MD, PhD

Dissecting the functional consequences of aberrant mRNA splicing by U2AF1(S34F) in hematologic malignancy

$30,000

2024

Laurent Gapin, PhD,

Enhancing T-Cell Therapy through PLZF Modulation

$30,000

2024

PI - Emily Blauel-Bocko, MD; Co-PI - Breelyn Wilky, MD

Elucidating exceptional responders to cabozantinib using a novel functional assay

$60,000

2024

Nathan A. Dahl, MD

Practical translation of proteosome inhibition for posterior-fossa ependymoma

$30,000

2024

Jean Mulcahy Levy, MD

Pre-clinical investigation to support IIT of CDK7 Inhibition in Pediatric Embryonal CNS tumors

$30,000

2024

Michael Verneris, MD

When CAR T Cells Fall Short: Leveraging CAR T Homing and Activation to Sensitize Tumors to Chemotherapy

$30,000

2024

Jay Hesselberth, PhD and Linda vanDyk, PhD

Immune Targeting therapies to disrupt virus-associated lymphomas

$60,000*

2023

Marisa R Moroney, MD

Assessing the HDAC2/MTA3 Complex as an Epigenetic Driver in Gynecologic Carcinosarcomas

$30,000

2023

Richard Blake Ross, MD

Enhancing Immune-Mediated Radiotherapy Efficacy in Murine models of Head and Neck Cancer through Peroxisome Proliferator-Activated Receptor Modulation

$30,000*

2023

Bethany Veo, PhD

Evaluating IDH1 facilitation of radiation resistance in MYC-amplified MB

$30,000

2023

Brad Haverkos, MD and Eduardo Davila, PhD

Leveraging Chemoimmunotherapy to improve treatments for newly diagnosed aggressive T-cell lymphomas

$60,000*

2023

Sujatha Venkataraman, PhD, Mark Eric Kohler, PhD and Rajeev Vibhakar, MD

Preclinical testing of gated CAR-T cells in overcoming tumor antigen escape for effective immunotherapy against DIPG

$60,000*

2023

Kaylyn Utley, M.B, B.Ch., BAO

Effect of p53 on CAR T cell efficacy against acute leukemia

$30,000

2023

Carlo Marchetti, PhD, Todd Pitts, PhD

To investigate the role of NLRP3 in Pancreatic Ductal Adenocarcinoma (PDAC)-associated chemotherapy tolerance

$60,000

2023

Masanori Hayashi, MD and Srinivas Ramachandran, PhD

Investigation of cell-free DNA to define EWG-FLI1 activity in Ewing Sarcoma

$60,000*

2023

Mayumi Fujita, MD, PhD and Dinoop Ravindran Menon, PhD

The role of H3k4me3 remodeling in melanoma BRAF/MEK inhibitor resistance

$60,000

2023

Quentin Vicens, PhD

Targeting the BMI1 oncogene mRNA using small molecules

$30,000

2023

Dong Wang, MS, PhD

Targeting CDK8 as a therapeutic approach for MYC driven medulloblastoma

$30,000

2023

Shi Biao Chia, PhD

Influenza virus infection in reawakening dormant metastatic breast tumor cells in the lung

$30,000

2023

Nathan A. Dahl, MD

Deconvoluting enhancer rewiring in giloma relapse following radiotherapy

$30,000*

2023

Peter Kabos, MD, Srinivas Ramachandran, PhD

Personalization of care for patients with advanced microsatellite stable colon cancer

$60,000

2023

Elena Shagisultanova, MD, PhD

Choosing the right target: comparing PIK3CA and AKT inhibition in HER2+PIK3CA-mutated breast cancer

$30,000

2023

John Tentler, PhD

Cancer Research Summer Fellowship Program

$30,000

2023

Katherine Lind, MD

A feasibility study of family interviews after early death in childhood cancer

$21,497

2023

Rui Zhao, PhD

Understanding and inhibiting the EYA3 and PP2A-B55a interaction in triple-negative breast cancer

$30,000

2023

Zhirui Wang, PhD, Rajeev Vibhakar, MD, PhD, Sujatha Venkataraman, PhD

Development of Novel Dual CD99/B7-H3 immunotoxins against DIPG, a fatal brain tumor in children

$60,000

2023

Rebecca Schweppe, PhD

The role of subcellular localization of FAK in thyroid cancer

$30,000

2023

Kristine Corkum, MD

Validation and Implementation of a pediatric Oncofertility Risk Calculator for Children Diagnosed with an Extracranial Solid Tumor

$29,867

2023

John Tentler, PhD

Cancer Research Summer Fellowship Program

$30,000

2022

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