RESEARCH GRANT AWARDS

Regulation of p53 in tanning

Exploiting mRNA translation inhibition for the treatment of relapsed/refractory multiple myeloma

Role of CDK7 in medulloblastoma

Targeting of stemness factors and fusion proteins in salivary gland cancers through inhibition of translation elongation

Defining MDC1 as a central regulator of estrogen receptor and DNA repair in lobular carcinoma

Targeting Kinetochore Dysfunction in Cancer Cells

X-Ray Acoustic Computed Tomography Guided Adaptive Radiotherapy

Mechanisms of TDM1/radiation-induced toxicity in brain metastases

Oncogenic Role of the Super Elongation Complex in H3K27M-mutant Diffuse Midline Glioma

Targeting Maternal Embryonic Leucine Zipper Kinase (MELK) in the first pre-clinical models of Adrenocortical Carcinoma

Targeting relapse leukemia stem cells through inhibition of NAD synthesis

Inhibition of Chromatin Assembly Factor 1 B to Reverse Leukemogenesis

IPS-derived, CAR-expressing Natural Killer Cells Targeting EGFR on Pediatric Sarcomas

Functional activation of low-affinity T cells in the tumor

Suppression of human CD8 T cell antigen receptor signaling and cytotoxic activity by lysophosphatidic acid

Investigating the role of MEK and non-canonical Wnt inhibition in altering the immune microenvironment in metastatic colorectal cancer

Role of CDK4 and CDK6 in gammaherpesvirus oncogenesis

Investigating the mechanisms of EHMT1/2-dependent PARP inhibitor resistance

Patient-centric Multi-Omics Approach to Identifying Actionable Therapeutics in Cancer

Improving immune checkpoint inhibitor efficacy by targeting myeloid-derived suppressor cell function

Diffusion tensor image tractography in surgical resection of glioblastoma resection and surgical safety

Elucidating mechanisms by which a newly developed HDAC inhibitor sensitizes B cell lymphomas to PD-1 therapy

Cancer Research Summer Fellowship Program

Cooperative Src and MAP Kinase Signaling in Thyroid Cancer

Targeting the Achilles heel of prostate cancer with loss of CHD1 and MAP3K7

Potentiating anti-PD1 Immunotherapy with Mitotane in Adrenocortical Carcinoma

Characterization of heterogeneous tumor subpopulations in childhood ependymoma

Patient Derived Tumor Organoids for Personalized and Targeted Colorectal Cancer Therapeutics

Storable, Thermally Activated, Self-Illuminating Nanoparticles Optical Imaging of Cancer

Targeting IL17 in Kras mutant lung cancer

Evaluation of Malgylcemia via Continuous Glucose monitoring in the Pediatric Hematopoietic Stem Cell Transplant Population

Cancer Research Summer Fellowship Program

Targeting FAK and Src in Thyroid Cancer

Exploiting apoptotic vulnerability in anti-estrogen response and resistance in invasive lobular carcinoma

Elucidate novel mechanisms of chemotherapy agent-treated lymphomas to activate immune responses

Improving targeted therapy in melanomas with BRAF fusions

Examining the role of c-Kit in metastasis of Invasive Lobular Breast Cancer

High-dimensional analysis of effector T cell mechanisms in lung cancer

Role of Six2 in mediating late stage metastasis

The epigenetic modifiers PHF2 and PhF8 in Ewing Sarcoma

Validating USP35 as an anticancer drug target

Systematic Alternative Splicing Analysis for Trancriptomic Misregulation in Cancer

Deregulation of mRNA 3′ end formation in breast cancer

Whole genome knockout screening to identify novel TERT regulators with prognostic relevance in bladder cancer patients

Comparison of Adult Adamantinomatous Craniopharyngioma Gene Expression with Known Pediatric Gene Expression

Enhancing the Effects of Immune Checkpoint Blockade with Radiation Therapy in Head and Neck Cancer

Validating CD123 as a Leukemia Stem Cell Marker and Therapeutic Target in Pediatric AML

Measuring chromosome-conformation abnormalities within a single cancer cell

Evaluating the role of pro-lymphangiogenic factor Sem7a in dampening anti-tumor immunity

Understanding how smoking alters selection for common oncogenic mutations in the genesis of lung cancer

Role of androgens on lipid catabolism in prostate cancer

Splicing gene mutations and infection in MDS patients

Investigating the role of MAML3 in neuroendocrine tumorigenesis

Targeting Eya2 to inhibit c-Myc driven Medulloblastoma Tumor

CARD10 and NFkB signaling in melanoma: Implications for immunotherapy

Exploiting Patient Derived Cancer Models for Novel Immunotherapy Regimens

Identification of TME-Derived Pathways for Co-Targeting in FGFR1-Dependent Lung Cancers

Mechanisms of Resistance to T Cell-Mediated Immunotherapy in Non-Small Cell Lung Cancer

Targeting paracrine stromal factors induced by P13K inhibitor therapy in head and neck cancer

Targeting the novel immune checkpoint CD112R for cancer therapy

Role of Antitumor Chemokines in Clearance of Head and Neck Cancer

Role of TRKB/BDNF axis in brain metastatic breast cancer

Role of microRNA methylation and its application as a biomarker in head and neck cancer

Examining oncogenic clonal expansions in the context of aging

Elucidating the Mechanism by which ESE-1 Controls Estrogen Mediated Tumorigenesis in HER2 + ER + Luminal B Human Breast Cancer

Cancer Research Summer Fellowship Program

Therapeutic targeting of organ specific tumor growth and metastases through functional genomics

Novel genes mediating cancer cell survival and proliferation in hypoxic conditions

The Role of ETV6 in B lymphopoiesis

p53 in melanoma

Examining the role of Mucin-2 in breast cancer

Integrating Transcriptional Regulatory And Metabolic Networks To Characterize Bladder Cancer Cellular Response to Chemotherapies

Determining the utility of UV photography as a quantitative tool for evaluating sun exposure history of children and adolescents

Cancer Research Summer Fellowship Program

Homozygously deleted chromosomal changes in metastatic melanoma