RESEARCH GRANT AWARDS

Combined ATRA and Ipillmuma treatment to reduce immunosuppression in melanoma patients

Role of PBRM1 mutation in clear cell renal cell carcinoma

Evaluation of pharmacologic inhibition of histone demethylases in Ewing Sarcoma

Developing stapled peptides for breast cancer theraphy

The effect of inhibiting splicing factor Snu114 in cancer

Grhl2 Developmental Network to Identify Novel Suppressors of EMT in Breast Cancer

Characterizing the activation status of inflammatory infiltrates in persistent and regressive premalignanat bronchial dysplasia

The function of tumor infiltrating B cells in non small cell lung cancer patients

Kinome Essential Screen for Discovery of Novel Targets in Small Cell Lung Cancer

Elucidating the roles of midbodies during squamous cell carcinoma progression

Novel Therapeutic Targets in Ezh2-Inactivated Acoute Leukemia

HAS2 is a critical effector for AGL mediated regulation of tumor growth

Targeting Src kinase with dasatinib in thryoid cancer

Autophagy and RIP#-dependent necrosis in cancer chemotherapy

The Roles of APOBEC3 in Human Papillomavirus Infection and Oncogenesis

Role of hypoxic signaling in influencing T cell mediated cancer immunotherapy

Unique patterns of progression in recurrent pediatric Ependymoma

Metabolomics of primary and recurrent high grade gilomas: a role for the UPR

In Vivo modeling of salivary gland tumor formation progression

Genomic sequencing-based predictive biomarker development for targeted anti- cancer therapies

AGL, a glycogen debranching gene is a novel suppressor of bladder cancer growth

Role of HIF in regulating RNI splicing of HIF target genes

H3K9 histone demethylases in Ewing Sarcoma

Novel allosteric inhibitors of Eya 2 phosphate for treatment of metastatic breast cancer

Targeting autophagy for the treatment of triple negative breast cancer

Collaborative Project to increase accrual to cancer trials

Discovery of novel targets for young patients with colorectal cancer

Profile specific HDAC inhibitors for triple negative breast cancer

A dose escalation study of Ibrutinib with Lenalidomide for relapsed and refractory chronic lymphocytic leukemia/small lymphocytic lymphoma

Regulating EGFR protein levels by a deubiquitinaying enzyme in cancer cells

Development of Antibody as immunotherapy for pediatric brain tumors

Cancer Research Fellowship Program

Targeting Vascular Endothelial Growth Factor C in the cancer stem like population sensitizes breast Ccncer cells to oxidize stress and onhibits tumor progression

Protein Kinase C Delta and breast cancer therapeutics

Targeting Melanoma Photocinogeneses by blocking C+BP1

Pre-Clinical Investigation of Treprostinil as a Cemopreventive Agent for non-small cell lung cancer

Bronchial Somatic Chromosomal Alterations in lung cancer risk

Effects of Androgen Deprivation Therapy on geriatric health and physical function in men over 70 years of age with prostate cancer

Defining the role of SF 381 mutations in Leukemia

Targeting the Kynurenine Pathway to inhibit breast cancer metastases

Investigating the role of lymphangiogenesis and lymphovascular invasion in metastasis of postpartum breast cancer

Development of an Improved Classifier for Predicting Multiple Drug Classes and Molecular Targets for Tumor Subtypes

Role of alternative polyadenylation in estrogen receptor positive breast cancer

Novel Lung Cancer Therapeutics

Metformin Inhibits Metastasis in Triple Negative Breast Cancer

Characterizing the Function and Location of B Cells in Lung Cancer

Tumor cell Dissemination and Metastasis Initiation in Head and Neck Cancer

The Role of Eya in breast cancer metastic progression

Epignetic induction of erbB2/erbB3-targeting miRNAs in breast cancer

Colorado Cancer Research Program

The Role of PHF1 in the repressive activity of PRC2

Autophagy Dependence and Chloroquine Sensitivity in Metastatic Cancer

Inhibiting the transcriptional co-repressor CtBP for cancer therapy using cell penetrating peptide

Dissection of the perforin pathway in cancer immunotherapy

Evaluating the Role of miR 193b in Ewing Sarcoma growth Suppression

Virus Manipulation of a Cellular Chromatin Modifying Complex

Regulation of lymphoma dissemination by the actin-myosin cytoskeleton

Monocyte Blockade with CCR2 Antagonists for Inhibition of tumor metastases

Acquired Resistance to ROS1 inhibition in Non-Small Cell Lung Cancer: Identification of Cellular Mechanisms and Exploration of Alternative Treatment Strategies

Defining the role of TAK1 in non-small cell lung cancer

2012 Cancer Research Summer Fellowship Program

Resistance of Human Head and Neck Squamous Cell Carcinoma to Concurrent EGFR and Radiotherapy Mediated Through the Hedgehog Pathway

Osteosarcoma: Biomarkers of Metastasis and Resistance to Therapy

Genome-wide RA interference screen for mediators of cell death induced by a novel vitamin D analog in triple negative breast cancer

PathCMap Development of pathway signature system for identifying partners of synethetic lethal genes

Tumor initiating and Drug Resistant Properties of a minor Population of Stem-Like Cells in Explant Models of Estrogen Receptor Positive Human Breast Tumors

LPA Regulation of T Cell Tumor Immunity

Cancer Research Summer Fellowship Program

High Throughput Functional Genetic Screening to Define the Role of Autophagy in Pediatric Brain Tumors

Competency Development to Reduce Obesity and Promote Long Term Survival Following treatment for Breast Cancer

Does cell surface transporter expression determine the response of breast cancer

PKCδ as a biomarker and regulator of response to chemotherapy in endometrial cancer

The regulation of MMP Secretion During the Invasion of Breast Cancer Cells

Identification of transcriptional cofactors that trigger alternations in breast cancer pathology and therapeutic response

Identifying mechanisms of resistance to the novel NAE inhibitor, MLN4924, in melanoma